5 Key Nutrients for Weight Loss Drugs

Weight loss pills? You may want to consider supplementing for the best health. This is why.

GLP-1 drugs such as Ozempic®, Wegovy® and Mounjaro® are becoming increasingly popular for their effectiveness in supporting weight loss. These drugs were originally developed to manage type 2 diabetes and worked by mimicking the action of a hormone called glucagon-like peptide-1 (GLP-1). In short, they help slow digestion, regulate blood sugar and curb appetite. Together, these results can help people reduce their calorie intake, which often leads to weight loss.

But this is most people No Realize: The same mechanisms that can help you lose weight can also lead to unexpected nutritional shortages.

As a registered dietitian, I have more and more clients asking, “Should I take vitamins with Ozempic?” The simple answer is, yes. Vitamins are one of the other key nutrients that should be included in any weight loss medication treatment plan.

This article explores why certain deficiencies on GLP-1 may be more likely to support the science of nutrition during the weight loss journey using these drugs.

Why does nutritional deficiency occur on GLP-1

GLP-1 receptor agonists work by slowing gastric emptying. In other words, food stays in the stomach for longer, which makes you feel full for a long time. While this is great for appetite control, it can also reduce the amount (and frequency) you eat. result? There are fewer calories, therefore, less nutrients – unless you really intentionally intentionally have something on the plate.

In a 2025 study, researchers found that GLP-1 users are more likely to be in a range of essential nutrients than non-users. These include:

These deficiencies are found in gender and in all age groups. In many cases, nutrient levels drop below clinically acceptable thresholds, and if unresolved, concerns arise about long-term health effects.

5 Key Nutrients to Watch While Taking Ozempic or Other GLP-1 Drugs

1. Vitamin B12

B12 plays a key role in energy metabolism, red blood cell production and nervous system function. Unfortunately, it is already a generally insufficient nutrient, especially among people over 50 and those who eat less meat. Since GLP-1 can reduce gastric acid and slow absorption, B12 levels can be further reduced.

Nutritionist tips: Look for a B12 supplement in the form of methylcobalamin to absorb better, or consider including at least 100% of your daily value (DV). Hum’s B12 Turbo might be a great addition, depending on your current intake.

2. iron

Iron is crucial for oxygen transport and energy. Low iron can make you feel tired, lack of breathing and even dizzy. Remember that many of these symptoms can easily be confused with “adjusting” new medications or lowering calorie diets.

Interestingly, premenopausal people are already at a higher risk of iron deficiency. However, with smaller meals and less red meat intake (which is the best source of iron), this risk increases as GLP-1 increases.

Nutritionist tips: If you’re always tired or cold, talk to your healthcare provider about checking your iron levels. If supplemented, consider Hum’s basic control, which provides 100% daily value for iron. Additionally, it provides other nutrients cited in the study, such as folic acid and magnesium.

3. Vitamin D

Sunshine vitamins do more than just support the bones. This is also crucial for a strong immune system, mood and even weight regulation. However, vitamin D is one of the most common defects in the United States

Nutritionist tips: Vitamin D3 is the most bioavailable form. Dosages of 1,000–2,000 IU per day are generally recommended, but blood levels (25 (OH)D) can help you personalize the dose. Hum’s There is here, and Sun can provide 2000 IU of plant-based vitamin D3 in a convenient daily soft gel.

4. protein

Although not micronutrients, protein deserves special shoutouts. GLP-1 drugs help reduce overall food intake, but they do not selectively suppress cravings. In fact, you may only eat less. This means you may be lacking in protein, this is:

• Save lean muscle mass
• Support metabolism
• Promotes satiety and blood sugar balance

Nutritionist tips: Target 20-30 grams of protein per meal. If whole foods alone are hard to hit, adding digestible-friendly protein powder can help you achieve your goals easily. Hum’s core strength is an excellent shirtless option and comes with a variety of amino acids.

5. fiber

GLP-1 drugs generally slowed down digestion. This can lead to one of the most common side effects people experience: violations. And, fiber intake is often hit when you eat less overall.

Fiber plays a key role in digestive health, blood sugar regulation and even cholesterol management. It also helps keep your bowel movements regular. Naturally, this is important when you deal with your tired gut.

Nutritionist tips: By combining fruits, vegetables, beans and whole grains, at least at least 25-30 grams of fiber per day. If you don’t necessarily get there, fiber supplements can help fill the gap. Hum’s Flatter Me Fiber is a great choice to provide prebiotic fibers to support digestion and regularity without causing swelling of some fiber powders.

Conclusion Weight loss medicine nutrients

GLP-1 drugs can be a powerful tool for weight loss, but they can also change your diet, digest and absorb nutrients. result? Higher lack of key vitamins and minerals is at a higher risk, keeping your body at its best.

The good news is that you don’t need to overhaul your diet overnight. With some targeted additions, whether through food, supplements, or smart multivitamins, you can stay on track on your GLP-1 journey.

As always, talk to your healthcare provider or nutritionist before starting any new supplements, especially when taking prescription weight loss pills.